Like conventional approaches in tissue engineering, bioprinting pursues the goal of the construction of physiological tissue in vitro. The printing process enables the individual setup of a wide variety of shapes and geometries. Especially the implementation of minimal sized structures benefit considerably from the manufacturing process. The automated assembly will also facilitate the expansion of production figures and the reduction of the needed production time and costs.

The Kluger-Lab is currently working on the conversion of classical tissue engineering construction methods into an additive manufacturing process. An extrusion-based printer is used for this purpose. Cells can be incorporated into natural polymers such as gelatine. The flow properties of this combination must be adapted accordingly to allow for the uniform printing into dimensionally stable constructions.

Currently, the work especially focuses on the development of human adipose tissue, which is urgently needed for the replacement of subcutaneous adipose tissue after severe burns or after tumor removal. Bioprinting is estimated to significantly improve the setup of supplying blood vessel structures. However, the transfer to a bioprinting construction is also being considered for other tissues.

Contact: Petra KlugerAnn-Cathrin Volz, Franziska Albrecht