M. Sc. Freia Schmidt


Building 2, room 006

Mail: Freia.schmidt@dont-want-spam.reutlingen-university.de

Research Projects

  • ImmuneFat2Skin
  • Fat2Skin


Since 08/2018: Scientist at the Reutlingen Research Institute 

Since 01/2015: PhD student at the University of Würzburg supervised by Prof. Dr. Heike Walles, Prof. Dr. Matthias Goebeler, Dr. Jan Hansmann and Dr. Florian Groeber-Becker 

08/2017 – 06/2018 Research Associate, Fraunhofer ISC, Würzburg

01/2013 – 08/2017 Research Associate, Translational Center Würzburg, Regenerative therapies in oncology and musculoskeletal disease, Branch of the Fraunhofer IGB, Würzburg

08/2013 – 12/2014 Research Associate, Fraunhofer IGB, Stuttgart

09/2011 – 07/2013: Biomedical Engineering (M. Sc.), University of Applied Sciences Albstadt-Sigmaringen

Master thesis: “Establishment of an osteoblast/osteoclast co-culture system to simulate the in vivo situation for testing iron-based bone replacement materials“ at the Fraunhofer IGB, Department CTE

03/2007 – 09/2011:Biotechnologie (B. Sc.), University of Applied Sciences Esslingen

Bachelor thesis: “Investigation of modified titanium substrates for endo-exo prostheses in terms of their interaction with human skin cells“ at the Fraunhofer IGB, Department CTE

Thematic Priorities

  • Skin Tissue Engineering
  • Melanoma
  • Automatization in Tissue Engineering
  • Co-culture systems
  • Cell-based test systems


Schmidt FF, Nowakowski S and Kluger PJ (2020) Improvement of a Three-Layered in vitro Skin Model for Topical Application of Irritating Substances. Front. Bioeng. Biotechnol. 8:388. doi: 10.3389/fbioe.2020.00388

F. F. Schmid*, C. Kleinhans*, F. V. Schmid, P. J. Kluger: Comparison of osteoclastogenesis and resorption activity of human osteoclasts on tissue culture polystyrene and on natural extracellular bone matrix in 2D and 3D; Journal of Biotechnology. 2015

F. F. Schmid, T. Schwarz, M. Klos, W. Schuberthan, H. Walles, J. Hansmann, F. K. Groeber: Applicability of a Dual-Arm Robotic System for Automated Downstream Analysis of Epidermal Models. Applied In Vitro Toxicology. 2016

C. Lotz, F. F. Schmid, A. Rossi, S.Kurdyn, D. Kampik, B. De Wever, H. Walles, F. K. Groeber:Alternative methods for the replacement of eye irritation testing; ALTEX. 2015

Groeber F, Engelhardt L, Lange J, Kurdyn S, Schmid FF, Rücker C, Mielke S, Walles H, Hansmann J:A first vascularized skin equivalent for as an alternative to animal experimentation; ALTEX. 2016

Groeber F, Schober L, Schmid FF, Traube A, Kolbus-Hernandez S, Daton K, Hoffmann S, Petersohn S, Schäfer-Korting M, Walles H., Mewes  :Catch-up validation study of an in vitro skin irritation test method based on an open source reconstructed epidermis (phase II), Toxicology in Vitro, Volume 36, 2016

Lotz C*, Schmid FF*, Oechsle E, Monaghan MG, Walles H, Groeber-Becker F: Cross-linked Collagen Hydrogel Matrix Resisting Contraction To Facilitate Full-Thickness Skin Equivalents, ACS Applied Materials & Interfaces, 2017

Rico Brendtke, Bart De Wever, Freia Schmid, Florian Groeber, Jan Hansmann, Heike Walles: High-Throughput Screening Techniques, in Alternatives for Dermal Toxicity Testing, C. Eskes, E. van Vliet, and H.I. Maibach, Editors. 2017, Springer International Publishing: Cham. p. 579-592.

Schmid FV, Kleinhans C, Schmid FF, Kluger PJ: Osteoclast Formation within a Human Co-Culture System on Bone Material as an In Vitro Model for Bone Remodeling Processes; JMFK, 2018

Schmid FF*, Grober-Becker F*, Schwab S, Thude S, Goebeler M, Walles H, Hansmann J: A standardized method based on pigmented epidermal models evaluates sensitivity against UV-irradiation; ALTEX, 2018

Lotz C., Kiesewetter L., Schmid FF., Hansmann J., Walles H., Groeber-Becker F: Replacing the Draize eye test: Impedance spectroscopy as a 3R method to discriminate between all GHS categories for eye irritation; Sci Rep, 2018

*equally contributed